张娜茹 博士
讲师
临床医学系教师
电话：19858186388 邮箱：zhangnr@zucc.edu.cn 办公地址：浙大城市学院北校区理2-419
研究方向：病毒免疫学
个人简介
张娜茹，讲师，曾在香港大学攻读博士学位，在美国纽约血液中心做博士后，到瑞典卡罗琳斯卡医学院做访问学者。主要从事呼吸道病毒（流感病毒和新型冠状病毒）疫苗相关研究，探究疫苗的免疫原性和保护效果，并阐明其具体的保护作用机制。曾主持中国博士后科学基金面上项目1项，杭州市留学回国人员创新项目1项，参与国家自然科学基金青年项目和面上项目各1项、浙江省自然科学基金3项。发表SCI论文近20篇。承担《医学微生物学》、《微生物学与免疫学》等本科生课程教学。荣获优秀班主任、优秀教职工等荣誉称号。
科研项目
1. 杭州市留学回国人员创新项目：类风湿关节炎治疗性疫苗的研究（2019-2022）
2. 中国博士后面上项目：针对亚洲RA患者的MHC-肽四聚体的构建及其临床应用研究（2016-2018）
发表论文
近五年代表文章
1.Kangchen Li, Qianting Ji, Shibo Jiang(*), Naru Zhang(*). Corrigendum: Advancement in the development of therapeutics against Zika virus infection. Frontiers in cellular and infection microbiology. 2022, 12:1006226.
2.季倩婷，尚浩天，施泽灿，郑天宇，姚佳薇，姜世勃*，张娜茹*. 新型冠状病毒疫苗的研究策略及应对奥密克戎等变异株的挑战[J/OL]. 病毒学报.2022, 1-11.
3.Naru Zhang(#), Qianting J(#)i, Zezhong Liu(#), Kaiming Tang, Yubin Xie, Kangchen Li, Jie Zhou, Sisi Li, Haotian Shang, Zecan Shi, Tianyu Zheng, Jiawei Yao, Lu Lu(*), Shuofeng Yuan(*), Shibo Jiang(*). Effect of different adjuvants on immune responses elicited by protein-based subunit vaccines against SARS-CoV-2 and its Delta variant. Viruses. 2022, 14(3), 507.
4.Naru Zhang(*), Kangchen Li, Zezhong Liu, Kutty Selva Nandakumar，Shibo Jiang(*).A perspective on the roles of adjuvants in developing highly potent COVID-19 vaccines. Viruses. 2022, 14(2), 387.
5.Kehui Zhou(#), Chaoqun Li(#), Wen Shi, Xiaodan Hu, Kutty Selva Nandakumar(*), Shibo Jiang(*), Naru Zhang(*). Current progress in the development of Zika virus vaccines. Vaccines (Basel). 2021, 9(9), 1004.
6.Qian Ou, Jiaqi Fang, Zhesheng Zhang, Zhe Chi, Jie Fang, Diyan Xu, Kaizhong Lu, Mengqing Qian, Dayong Zhang, Junping Guo, Wei Gao, Naru Zhang, Jianping Pan(*). TcpC inhibits neutrophil extracellular trap formation by enhancing ubiquitination mediated degradation of peptidylarginine deiminase 4. Nature Communication. 2021, 12(1):3481.
7.Naru Zhang, Jian Shang, Chaoqun Li, Kehui Zhou, Lanying Du(*).An overview of Middle East respiratory syndrome coronavirus vaccines in preclinical studies. Expert Review of Vaccines. 2020, 19(9): 817-829.
8.Naru Zhang, Chaoqun Li, Shibo Jiang(*), Lanying Du(*).Recent advances in the development of virus-like particle-based flavivirus vaccines. Vaccines (Basel). 2020, 8(3): 481.
9.Naru Zhang, Chaoqun Li, Yue Hu, Kangchen Li, Jintian Liang, Lili Wang, Lanying Du(*), Shibo Jiang(*).Current development of COVID-19 diagnostics, vaccines and therapeutics. Microbes and Infection. 2020, 22(6-7): 231-235.
10.Naru Zhang, Lili Wang, Xiaoqian Deng, Ruiying Liang, Meng Su, Chen He, Lanfang Hu, Yudan Su, Jing Ren, Fei Yu(*), Langying Du(*), Shibo Jiang(*). Recent advances in the detection of respiratory virus infection in humans. Journal of Medical Virology. 2020, 92(4):408-417.
11.Ruiying Liang(#), Lili Wang(#), Naru Zhang(#), Xiaoqian Deng, Meng Su, Yudan Su, Lanfang Hu, Chen He, Tianlei Ying(*), Shibo Jiang(*), Fei Yu(*). Development of small-molecule MERS-CoV inhibitors. Viruses. 2018, 10(12): E721.
12.Cecilia Lindgren, Mohit Tyagi, Johan Viljanen, Johannes Toms, Changrong Ge, Naru Zhang, Rikard Holmdahl, Jan Kihlberg, Anna Linusson. Dynamics determine signaling in a multicomponent system associated with rheumatoid arthritis. Journal of Medicinal Chemistry. 2018, 61(11): 4774-4790.
13.Naru Zhang, Kutty Selva Nandakumar. Recent advances in the development of vaccines for chronic inflammatory autoimmune diseases. Vaccine. 2018, 36(23): 3208-3220.
教学与课程
目前担任本科生课程：《医学微生物学》、《微生物学与免疫学》的理论及实验课的本科教学。
奖励荣誉
1. 2022年：浙江省第十四届大学生生命科学竞赛（指导老师）二等奖；浙大城市学院课程思政优秀案例
2. 2021年：医学院课程思政典型案例二等奖
3. 2020-2021学年：优秀班主任
4. 2019-2020学年；2020-2021学年：浙大城市学院教学质量二等奖
5. 2019年：浙大城市学院青年教师教学竞赛三等奖
社会兼职
浙江省免疫学会委员
